Pub. Date : 2016 Jul
PMID : 27129925
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Stimulation by pro-apoptotic valinomycin of cytosolic NADH/cytochrome c electron transport pathway-Effect of SH reagents. | Valinomycin | cytochrome c, somatic | Homo sapiens |
| 2 | Valinomycin at 2nM stimulates both the energy-dependent reversible mitochondrial swelling and the NADH/cyto-c oxidation pathway. | Valinomycin | cytochrome c, somatic | Homo sapiens |
| 3 | The pro-apoptotic activity of valinomycin, as well as to the dissipation of membrane potential, can be also ascribed to the increased activity of the NADH/cyto-c oxidation pathway useful as an additional source of energy for apoptosis. | Valinomycin | cytochrome c, somatic | Homo sapiens |
| 4 | It can be speculated that the activation of the NADH/cyto-c system coupled to valinomycin-induced mitochondrial osmotic swelling may represent a strategy to activate apoptosis in confined solid tumours. | Valinomycin | cytochrome c, somatic | Homo sapiens |