Title : NSs Virulence Factor of Rift Valley Fever Virus Engages the F-Box Proteins FBXW11 and β-TRCP1 To Degrade the Antiviral Protein Kinase PKR.

Pub. Date : 2016 Jul 1

PMID : 27122577






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Consequently, NSs was found to interact with both FBXW11 and beta-TRCP1. 5'-O-[N-(L-ASPARAGINYL)SULFAMOYL]ADENOSINE F-box and WD repeat domain containing 11 Homo sapiens
2 Thus, NSs eliminates the antiviral kinase PKR by recruitment of SCF-type E3 ubiquitin ligases containing FBXW11 and beta-TRCP1 as substrate recognition subunits. 5'-O-[N-(L-ASPARAGINYL)SULFAMOYL]ADENOSINE F-box and WD repeat domain containing 11 Homo sapiens