Title : MALT1 inhibitors prevent the development of DSS-induced experimental colitis in mice via inhibiting NF-κB and NLRP3 inflammasome activation.

Pub. Date : 2016 May 24

PMID : 27105502






1 Functional Relationships(s)
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1 The in vitro study showed that MALT1 inhibitors decreased production of IL-1beta/IL-18 in phorbol myristate acetate-differentiated THP-1 cells and bone marrow derived macrophage via suppressing the activation of NF-kappaB and NLRP3 inflammasome. Tetradecanoylphorbol Acetate interleukin 1 beta Homo sapiens