Pub. Date : 2016 May 15
PMID : 27101925
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Furthermore, diosmetin remarkably inhibited TGF-beta1-induced phosphorylation of phosphoinositide 3-kinase (PI3K)/Akt and mitogen activated protein kinase (MAPK) pathways in HBE cells. | diosmetin | AKT serine/threonine kinase 1 | Homo sapiens |
2 | SIGNIFICANCE: Our results demonstrate for the first time that diosmetin alleviates TGF-beta1-induced EMT by inhibiting ROS generation and inactivating PI3K/Akt and MAPK pathways. | diosmetin | AKT serine/threonine kinase 1 | Homo sapiens |