Pub. Date : 2016 Jun 1
PMID : 27100819
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | While there has been limited success in inhibiting the protein directly, phase 2 and phase 3 clinical trials have demonstrated success in inhibiting downstream effectors, specifically MEK1 and/or MEK2 with selumetinib and trametinib (albeit with poor tolerability). | AZD 6244 | mitogen-activated protein kinase kinase 2 | Homo sapiens |