Title : Enhancing doxorubicin efficacy through inhibition of aspartate transaminase in triple-negative breast cancer cells.

Pub. Date : 2016 May 13

PMID : 27086848






1 Functional Relationships(s)
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1 Triple-negative breast cancer (TNBC) cell lines are identified to overexpress aspartate transaminase (GOT1), which can potentially control the intracellular levels of reactive oxygen species (ROS) through NADPH synthesis and enhances tumor growth. NADP glutamic-oxaloacetic transaminase 1 Homo sapiens