Title : Development of carbon-11 labeled acryl amides for selective PET imaging of active tissue transglutaminase.

Pub. Date : 2016 Apr

PMID : 27067043






1 Functional Relationships(s)
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1 INTRODUCTION: Tissue transglutaminase (TG2) is a ubiquitously expressed enzyme capable of forming metabolically and mechanically stable crosslinks between the gamma-carboxamide of a glutamine acyl-acceptor substrate and the epsilon-amino functionality of a lysine acyl-donor substrate resulting in protein oligomers. Lysine transglutaminase 2 Homo sapiens