Title : Activation of the PI3K/mTOR Pathway following PARP Inhibition in Small Cell Lung Cancer.

Pub. Date : 2016

PMID : 27055253






1 Functional Relationships(s)
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1 Using reverse-phase protein array, we found the proteins most significantly upregulated following treatment with the PARP inhibitors olaparib and rucaparib were in the PI3K/mTOR pathway (p-mTOR, p-AKT, and pS6) (p<=0.02). rucaparib taste 2 receptor member 63 pseudogene Homo sapiens