Title : Naringin attenuates granule cell dispersion in the dentate gyrus in a mouse model of temporal lobe epilepsy.

Pub. Date : 2016 Jul

PMID : 27040812






2 Functional Relationships(s)
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1 To clarify whether naringin treatment reduces GCD, we evaluated the effects of intraperitoneal injection of naringin on GCD and activation of mammalian target of rapamycin complex 1 (mTORC1), an important regulator of GCD, following intrahippocampal injection of KA. naringin CREB regulated transcription coactivator 1 Mus musculus
2 These results suggest that naringin treatment may help prevent epilepsy-induced hippocampal injury by inhibiting mTORC1 activation and thereby reducing GCD in the hippocampus in vivo. naringin CREB regulated transcription coactivator 1 Mus musculus