Title : [Pemetrexed + Sorafenib] lethality is increased by inhibition of ERBB1/2/3-PI3K-NFκB compensatory survival signaling.

Pub. Date : 2016 Apr 26

PMID : 27015562






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Sorafenib inhibited HSP90 and HSP70 chaperone ATPase activities and reduced the interactions of chaperones with clients including c-MYC, CDC37 and MCL-1. Sorafenib dynein axonemal heavy chain 8 Homo sapiens