Title : Polyamine Antagonist Therapies Inhibit Neuroblastoma Initiation and Progression.

Pub. Date : 2016 Sep 1

PMID : 27012811






1 Functional Relationships(s)
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1 Furthermore, the combination of DFMO with celecoxib was found to be highly active, alone, and combined with numerous chemotherapy regimens, in regressing established tumors in both models, including tumors harboring highest risk genetic lesions such as MYCN amplification, ALK mutation, and TP53 mutation with multidrug resistance. Celecoxib transformation related protein 53 Mus musculus