Title : Targeting Thioredoxin Reductase by Parthenolide Contributes to Inducing Apoptosis of HeLa Cells.

Pub. Date : 2016 May 6

PMID : 27002142






1 Functional Relationships(s)
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1 We reported here that PTL interacts with both cytosolic thioredoxin reductase (TrxR1) and mitochondrial thioredoxin reductase (TrxR2), two ubiquitous selenocysteine-containing antioxidant enzymes, to elicit reactive oxygen species-mediated apoptosis in HeLa cells. Reactive Oxygen Species thioredoxin Homo sapiens