Title : Effects of acrolein on the production of corticosterone in male rats.

Pub. Date : 2016 Jul

PMID : 26996390






3 Functional Relationships(s)
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1 Further investigating the steroidogenic pathway, the protein expressions of steroidogenic acute regulatory protein (StAR) and the upper receptor-melanocortin 2 receptor (MC2R) were attenuated in acrolein-treated groups. Acrolein melanocortin 2 receptor Rattus norvegicus
2 Further investigating the steroidogenic pathway, the protein expressions of steroidogenic acute regulatory protein (StAR) and the upper receptor-melanocortin 2 receptor (MC2R) were attenuated in acrolein-treated groups. Acrolein melanocortin 2 receptor Rattus norvegicus
3 These results suggested that acrolein decreased the releasing ability of corticosterone via an inhibition on the response of ZFR cells to ACTH and the reduction of protein expressions of StAR and MC2R as well as the activity of P450scc in rat ZFR cells. Acrolein melanocortin 2 receptor Rattus norvegicus