Title : Novel Oxindole Sulfonamides and Sulfamides: EPZ031686, the First Orally Bioavailable Small Molecule SMYD3 Inhibitor.

Pub. Date : 2016 Feb 11

PMID : 26985287






1 Functional Relationships(s)
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1 Potency optimization afforded two tool compounds, sulfonamide EPZ031686 and sulfamide EPZ030456, with cellular potency at a level sufficient to probe the in vitro biology of SMYD3 inhibition. fusarubin SET and MYND domain containing 3 Mus musculus