Title : MR spectroscopy for in vivo assessment of the oncometabolite 2-hydroxyglutarate and its effects on cellular metabolism in human brain gliomas at 9.4T.

Pub. Date : 2016 Oct

PMID : 26970248






1 Functional Relationships(s)
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1 We also observed significantly reduced glutathione (GSH) levels (39%, P = 0.019), which could be similarly caused by depletion of dihydronicotinamide-adenine dinucleotide phosphate (NADPH) during this conversion in IDH mutant gliomas. NADP isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens