Title : Soybean Ferritin Expression in Saccharomyces cerevisiae Modulates Iron Accumulation and Resistance to Elevated Iron Concentrations.

Pub. Date : 2016 May 15

PMID : 26969708






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1 Soybean Ferritin Expression in Saccharomyces cerevisiae Modulates Iron Accumulation and Resistance to Elevated Iron Concentrations. Iron ferritin-1, chloroplastic Glycine max
2 Soybean Ferritin Expression in Saccharomyces cerevisiae Modulates Iron Accumulation and Resistance to Elevated Iron Concentrations. Iron ferritin-1, chloroplastic Glycine max
3 This work explored how plant ferritin expression influenced baker"s yeast iron metabolism. Iron ferritin-1, chloroplastic Glycine max
4 Soybean ferritin protected yeast cells that lacked the Ccc1 vacuolar iron detoxification transporter from toxic iron levels by reducing cellular oxidation, thus allowing growth at high iron concentrations. Iron ferritin-1, chloroplastic Glycine max
5 Soybean ferritin protected yeast cells that lacked the Ccc1 vacuolar iron detoxification transporter from toxic iron levels by reducing cellular oxidation, thus allowing growth at high iron concentrations. Iron ferritin-1, chloroplastic Glycine max
6 Interestingly, when simultaneously expressed in ccc1Delta cells, SFerH1 and SFerH2 assembled as heteropolymers, which further increased iron resistance and reduced the oxidative stress produced by excess iron compared to ferritin homopolymer complexes. Iron ferritin-1, chloroplastic Glycine max
7 Interestingly, when simultaneously expressed in ccc1Delta cells, SFerH1 and SFerH2 assembled as heteropolymers, which further increased iron resistance and reduced the oxidative stress produced by excess iron compared to ferritin homopolymer complexes. Iron ferritin-1, chloroplastic Glycine max
8 Finally, soybean ferritin expression led to increased iron accumulation in both wild-type and ccc1Delta yeast cells at certain environmental iron concentrations. Iron ferritin-1, chloroplastic Glycine max
9 Finally, soybean ferritin expression led to increased iron accumulation in both wild-type and ccc1Delta yeast cells at certain environmental iron concentrations. Iron ferritin-1, chloroplastic Glycine max
10 Animals and plants possess large ferritin complexes that accumulate, detoxify, or buffer excess cellular iron. Iron ferritin-1, chloroplastic Glycine max
11 Here, we explored how soybean ferritin expression influenced yeast iron metabolism, confirming that yeasts that express soybean seed ferritin could be explored as a novel strategy to increase dietary iron absorption. Iron ferritin-1, chloroplastic Glycine max
12 Here, we explored how soybean ferritin expression influenced yeast iron metabolism, confirming that yeasts that express soybean seed ferritin could be explored as a novel strategy to increase dietary iron absorption. Iron ferritin-1, chloroplastic Glycine max
13 Here, we explored how soybean ferritin expression influenced yeast iron metabolism, confirming that yeasts that express soybean seed ferritin could be explored as a novel strategy to increase dietary iron absorption. Iron ferritin-1, chloroplastic Glycine max