Title : Epac-protein kinase C alpha signaling in purinergic P2X3R-mediated hyperalgesia after inflammation.

Pub. Date : 2016 Jul

PMID : 26963850






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The expression of both Epac1 and Epac2 and the level of cAMP in DRGs are greatly enhanced after complete Freund adjuvant (CFA)-induced inflammation. complete freund adjuvant Rap guanine nucleotide exchange factor 3 Rattus norvegicus
2 Complete Freund adjuvant (CFA)-induced P2X3R-mediated hyperalgesia is not only blocked by Epac antagonists but also by the classical PKC isoform inhibitors, Go6976, and PKCalpha-siRNA. complete freund adjuvant Rap guanine nucleotide exchange factor 3 Rattus norvegicus