Title : Diagnostic FDG and FDOPA positron emission tomography scans distinguish the genomic type and treatment outcome of neuroblastoma.

Pub. Date : 2016 Apr 5

PMID : 26959748






2 Functional Relationships(s)
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1 Meanwhile, the ratio between FDG and FDOPA SUV(max) (G:D) correlated positively with HK2 (Spearman"s rho = 0.86, P < 0.0001) and negatively with DDC (rho = -0.58, P = 0.02) gene expression levels, which might suggest higher glycolytic activity and less catecholaminergic differentiation in NB tumors taking up higher FDG and lower FDOPA. Fluorodeoxyglucose F18 hexokinase 2 Homo sapiens
2 Meanwhile, the ratio between FDG and FDOPA SUV(max) (G:D) correlated positively with HK2 (Spearman"s rho = 0.86, P < 0.0001) and negatively with DDC (rho = -0.58, P = 0.02) gene expression levels, which might suggest higher glycolytic activity and less catecholaminergic differentiation in NB tumors taking up higher FDG and lower FDOPA. Fluorodeoxyglucose F18 hexokinase 2 Homo sapiens