Pub. Date : 2016 Sep
PMID : 26957211
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Epigallocatechin-3-gallate ameliorates autoimmune arthritis by reciprocal regulation of T helper-17 regulatory T cells and inhibition of osteoclastogenesis by inhibiting STAT3 signaling. | epigallocatechin gallate | signal transducer and activator of transcription 3 | Mus musculus |
| 2 | The expression of cytokines, oxidative stress proteins, and phosphorylated-signal transducer and activator of transcription-3, 705 and 727, were significantly less in mice treated with epigallocatechin-3-gallate than it was in controls. | epigallocatechin gallate | signal transducer and activator of transcription 3 | Mus musculus |
| 3 | At the molecular level, the antiarthritic effects of epigallocatechin-3-gallate may be due to induction of phosphorylated-extracellular signal-regulated kinase, nuclear respiratory factor 2, and heme oxygenase-1 and inhibition of signal transducer and activator of transcription-3 activation. | epigallocatechin gallate | signal transducer and activator of transcription 3 | Mus musculus |