Pub. Date : 2016 Feb
PMID : 26956973
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We observed that metformin decreased c-Myc levels, and ectopic expression of c-Myc blocked the effect of metformin on TTP expression and cell proliferation. | Metformin | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |
| 2 | We observed that metformin decreased c-Myc levels, and ectopic expression of c-Myc blocked the effect of metformin on TTP expression and cell proliferation. | Metformin | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |
| 3 | Our data indicate that metformin induces TTP expression by reducing the expression of c-Myc, suggesting a new model whereby TTP acts as a mediator of metformin"s anti-proliferative activity in cancer cells. | Metformin | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |
| 4 | Our data indicate that metformin induces TTP expression by reducing the expression of c-Myc, suggesting a new model whereby TTP acts as a mediator of metformin"s anti-proliferative activity in cancer cells. | Metformin | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |