Title : Tristetraprolin mediates the anti-proliferative effects of metformin in breast cancer cells.

Pub. Date : 2016 Feb

PMID : 26956973






2 Functional Relationships(s)
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1 p53 wild-type and p53 mutant breast cancer cells were treated with metformin, and expression of TTP and c-Myc was analyzed by semi-quantitative RT-PCR, Western blots, and promoter activity assay. Metformin tumor protein p53 Homo sapiens
2 Metformin induces the expression of tristetraprolin (TTP) in breast cancer cells in a p53-independent manner. Metformin tumor protein p53 Homo sapiens