Pub. Date : 2016 May 1
PMID : 26950191
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Western blot analyses revealed the rapid activation of Akt (Ser473) and p70S6K (Thr389) in ATRA-treated mASCs, and that levels of phosphorylated p70S6K were noticeably reduced in HtrA1-deficient mASCs. | Tretinoin | ribosomal protein S6 kinase, polypeptide 1 | Mus musculus |
| 2 | Western blot analyses revealed the rapid activation of Akt (Ser473) and p70S6K (Thr389) in ATRA-treated mASCs, and that levels of phosphorylated p70S6K were noticeably reduced in HtrA1-deficient mASCs. | Tretinoin | ribosomal protein S6 kinase, polypeptide 1 | Mus musculus |
| 3 | Further studies using mTOR inhibitor rapamycin and siRNA specific for the p70S6K gene Rps6kb1 confirmed ATRA-mediated mASC osteogenesis as being dependent on p70S6K activation. | Tretinoin | ribosomal protein S6 kinase, polypeptide 1 | Mus musculus |
| 4 | Further studies using mTOR inhibitor rapamycin and siRNA specific for the p70S6K gene Rps6kb1 confirmed ATRA-mediated mASC osteogenesis as being dependent on p70S6K activation. | Tretinoin | ribosomal protein S6 kinase, polypeptide 1 | Mus musculus |
| 5 | Further studies using mTOR inhibitor rapamycin and siRNA specific for the p70S6K gene Rps6kb1 confirmed ATRA-mediated mASC osteogenesis as being dependent on p70S6K activation. | Tretinoin | ribosomal protein S6 kinase, polypeptide 1 | Mus musculus |