Title : Synthesis, structural characterization, docking, lipophilicity and cytotoxicity of 1-[(1R)-1-(6-fluoro-1,3-benzothiazol-2-yl)ethyl]-3-alkyl carbamates, novel acetylcholinesterase and butyrylcholinesterase pseudo-irreversible inhibitors.

Pub. Date : 2016 Apr 1

PMID : 26947959






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Compounds indicated as 3b, 3d, 3l and 3n showed the best AChE inhibitory activity of all the evaluated compounds and were up to tenfold more potent than standard drug rivastigmine. Rivastigmine acetylcholinesterase (Cartwright blood group) Homo sapiens