Title : PLA2G5 regulates transglutaminase activity of human IL-4-activated M2 macrophages through PGE2 generation.

Pub. Date : 2016 Jul

PMID : 26936936






2 Functional Relationships(s)
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1 PLA2G5 regulates transglutaminase activity of human IL-4-activated M2 macrophages through PGE2 generation. Dinoprostone interleukin 4 Homo sapiens
2 Thus, our study shows a novel function of group V phospholipase A2 in regulating the transglutaminase activity of human interleukin-4-activated M2 macrophages through prostaglandin E2 generation and suggests that group V phospholipase A2 is a functionally relevant enzyme that may have therapeutic value for the treatment of human T-helper-2 inflammatory disorders. Dinoprostone interleukin 4 Homo sapiens