Pub. Date : 2016 Jun
PMID : 26928355
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We demonstrated that the inhibition of CPT-induced MDC1 foci formation by PG was caused by the direct suppression of histone H2AX phosphorylation at Ser139 (gammaH2AX), which is required for MDC1 foci formation, by quantifying gammaH2AX in cells and in vitro 9-AA also directly suppressed H2AX Ser139-phosphorylation in vitro but the concentration was much higher than that required to suppress CPT-induced MDC1 foci formation in cells. | gammah2ax | H2A.X variant histone | Homo sapiens |