Pub. Date : 2016 Jun
PMID : 26921685
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The cyclophilin-inhibitor alisporivir stimulates antigen presentation thereby promoting antigen-specific CD8(+) T cell activation. | alisporivir | CD8a molecule | Homo sapiens |
| 2 | Alisporivir pretreatment stimulated antigen presentation by hepatoma target cells, leading to enhancement of antigen-specific CD8(+) T cell activation by 40%. | alisporivir | CD8a molecule | Homo sapiens |
| 3 | CONCLUSIONS: Alisporivir stimulates antigen presentation by inducing enhanced MHC-I surface expression, thereby promoting antigen-specific CD8(+) T cell activation. | alisporivir | CD8a molecule | Homo sapiens |