Pub. Date : 2016 Mar 22
PMID : 26909611
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The CDK4/6 inhibitor LY2835219 has potent activity in combination with mTOR inhibitor in head and neck squamous cell carcinoma. | abemaciclib | cyclin dependent kinase 4 | Homo sapiens |
| 2 | Here, we report the antiproliferative activity of LY2835219, a selective CDK4/6 inhibitor through inhibition of CDK4/6-dependent Ser780 phosphorylation in retinoblastoma (RB) and induction of cell cycle arrest in HNSCC cells. | abemaciclib | cyclin dependent kinase 4 | Homo sapiens |
| 3 | Here, we report the antiproliferative activity of LY2835219, a selective CDK4/6 inhibitor through inhibition of CDK4/6-dependent Ser780 phosphorylation in retinoblastoma (RB) and induction of cell cycle arrest in HNSCC cells. | abemaciclib | cyclin dependent kinase 4 | Homo sapiens |