Title : Tel1 and Rif2 Regulate MRX Functions in End-Tethering and Repair of DNA Double-Strand Breaks.

Pub. Date : 2016 Feb

PMID : 26901759






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The cellular response to DNA double-strand breaks (DSBs) is initiated by the MRX/MRN complex (Mre11-Rad50-Xrs2 in yeast; Mre11-Rad50-Nbs1 in mammals), which recruits the checkpoint kinase Tel1/ATM to DSBs. dsbs MRX complex DNA-binding subunit Saccharomyces cerevisiae S288C
2 The cellular response to DNA double-strand breaks (DSBs) is initiated by the MRX/MRN complex (Mre11-Rad50-Xrs2 in yeast; Mre11-Rad50-Nbs1 in mammals), which recruits the checkpoint kinase Tel1/ATM to DSBs. dsbs MRX complex DNA-binding subunit Saccharomyces cerevisiae S288C