Pub. Date : 2016
PMID : 26901413
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | IL-17 Induction by ArtinM is Due to Stimulation of IL-23 and IL-1 Release and/or Interaction with CD3 in CD4+ T Cells. | artinm | interleukin 1 complex | Mus musculus |
2 | Furthermore, we showed that ArtinM directly induced the IL-23 mRNA expression and the IL-1 production by macrophages. | artinm | interleukin 1 complex | Mus musculus |
3 | In conclusion, ArtinM stimulates the production of IL-17 by CD4+ T cells in two major ways: (I) through the induction of IL-23 and IL-1 by APCs and (II) through the direct interaction with CD3 on the CD4+ T cells. | artinm | interleukin 1 complex | Mus musculus |