Title : Rho kinase inhibition following traumatic brain injury in mice promotes functional improvement and acute neuron survival but has little effect on neurogenesis, glial responses or neuroinflammation.

Pub. Date : 2016 May

PMID : 26896832






1 Functional Relationships(s)
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1 Mice subjected to a moderately severe TBI were treated for 1 or 4 weeks with the Rho kinase inhibitor Y27632, and functional outcomes and neuronal and glial cell responses were analysed at 1, 7 and 35 days post-injury. Y 27632 Rho-associated coiled-coil containing protein kinase 2 Mus musculus