Title : Salinomycin suppresses TGF-β1-induced epithelial-to-mesenchymal transition in MCF-7 human breast cancer cells.

Pub. Date : 2016 Mar 25

PMID : 26896736






1 Functional Relationships(s)
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1 Sal was able to inhibit TGF-beta1-induced EMT phenotypic transition and the activation of key signaling molecules involved in Smad (p-Smad2/3,Snail1) and non-Smad (beta-catenin, p-p38 MAPK) signals which cooperatively regulate the induction of EMT. salinomycin snail family transcriptional repressor 1 Homo sapiens