Title : DDX3 promotes tumor invasion in colorectal cancer via the CK1ε/Dvl2 axis.

Pub. Date : 2016 Feb 19

PMID : 26892600






2 Functional Relationships(s)
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1 Therefore, we hypothesized that DDX3 might promote tumor invasion via the CK1epsilon/Dvl2 axis due to beta-catenin/TCF activation. tcf DEAD-box helicase 3 X-linked Homo sapiens
2 The invasion capability in colon cancer cells and xenograft lung tumor nodules induced by a DDX3-overexpressing T84 stable clone in tail-vein injection model were nearly suppressed by inhibitors of CK1epsilon (PF4800567) and beta-catenin/TCF signaling (XAV939). tcf DEAD-box helicase 3 X-linked Homo sapiens