Pub. Date : 2016 Jun
PMID : 26890278
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Amiloride Analogs as ASIC1a Inhibitors. | Amiloride | acid-sensing (proton-gated) ion channel 1 | Mus musculus |
| 2 | AIMS: We examined the inhibitory effects of a number of amiloride analogs on ASIC1a currents, aimed at understanding the structure-activity relationship and identifying potent ASIC1a inhibitors for stroke intervention. | Amiloride | acid-sensing (proton-gated) ion channel 1 | Mus musculus |
| 3 | In addition, amiloride and its analogs inhibit ASIC currents in cortical neurons with the same potency rank order. | Amiloride | acid-sensing (proton-gated) ion channel 1 | Mus musculus |
| 4 | Among the tested amiloride analogs, benzamil is the most potent ASIC1a inhibitor. | Amiloride | acid-sensing (proton-gated) ion channel 1 | Mus musculus |