Pub. Date : 2016
PMID : 26881079
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We aimed to investigate the possible effects of melatonin on gene expressions and activities of MnSOD and catalase under conditions of oxidative stress induced by hydrogen peroxide (H2O2) in peripheral blood mononuclear cells (PBMCs). | Melatonin | catalase | Homo sapiens |
| 2 | Melatonin treatment of PBMCs caused a significant upregulation of catalase by almost 2-fold in comparison with untreated cells. | Melatonin | catalase | Homo sapiens |
| 3 | Moreover, pretreatment of PBMCs with melatonin resulted in a significant 1.8-fold increase in catalase expression compared to PBMCs treated only with H2O2. | Melatonin | catalase | Homo sapiens |
| 4 | Moreover, melatonin could promote inductive effect of H2O2 on catalase mRNA expression. | Melatonin | catalase | Homo sapiens |