Title : Limited efficacy of COX-2 inhibitors on nerve growth factor and metalloproteinases expressions in human synovial fibroblasts.

Pub. Date : 2016 May

PMID : 26876621






1 Functional Relationships(s)
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1 This study suggests the feedback roles of PGE2 in the negative regulation of NGF and MMP-1 and MMP-13 and the positive regulation of ADAMTS-4 and ADAMTS-5. Dinoprostone ADAM metallopeptidase with thrombospondin type 1 motif 5 Homo sapiens