Pub. Date : 2016 Jun
PMID : 26876595
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | DLST is the E2 transferase of the alpha-ketoglutarate (alpha-KG) dehydrogenase complex (KGDHC), which converts alpha-KG to succinyl-CoA in the TCA cycle. | Tricarboxylic Acids | dihydrolipoamide S-succinyltransferase | Homo sapiens |
| 2 | Polar metabolomics profiling revealed that the TCA cycle was disrupted by DLST knockdown in human T-ALL cells, as demonstrated by an accumulation of alpha-KG and a decrease of succinyl-CoA. | Tricarboxylic Acids | dihydrolipoamide S-succinyltransferase | Homo sapiens |