Title : Effect of N-Terminal Extension of Cardiac Troponin I on the Ca(2+) Regulation of ATP Binding and ADP Dissociation of Myosin II in Native Cardiac Myofibrils.

Pub. Date : 2016 Mar 29

PMID : 26862665






2 Functional Relationships(s)
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1 To investigate which step(s) of the ATPase cycle is regulated by the N-terminal extension of cTnI, here we studied the calcium dependence of cardiac myosin II ATPase kinetics in isolated cardiac myofibrils. Calcium dynein, axonemal, heavy chain 8 Mus musculus
2 These data from experiments using native cardiac myofibrils under physiological conditions indicate that modification of the N-terminal extension of cTnI plays a role in the calcium regulation of the kinetics of actomyosin ATPase. Calcium dynein, axonemal, heavy chain 8 Mus musculus