Title : Total Synthesis of a Diacetonide Derivative of Thuggacin A.

Pub. Date : 2016 Mar 4

PMID : 26856208






1 Functional Relationships(s)
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1 The synthesis features the stereoselective Stille cross-coupling reaction to set up the whole carbon framework, aldol condensation to construct the highly substituted conjugated diene, non-Evans syn aldol, CBS reduction, Hantzsch"s thiazole synthesis, Horner-Wadsworth-Emmons reaction, and Shiina"s macrolactonization. diene synemin Homo sapiens