Pub. Date : 2016
PMID : 26848974
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Integrin Ligation Results in Nephrin Tyrosine Phosphorylation In Vitro. | Tyrosine | NPHS1 adhesion molecule, nephrin | Homo sapiens |
2 | However, proximal signaling events that result in nephrin tyrosine phosphorylation are not well understood. | Tyrosine | NPHS1 adhesion molecule, nephrin | Homo sapiens |
3 | Nephrin is tyrosine phosphorylation-silent in healthy glomeruli when presumably the nephrin extracellular domain is in an engaged state. | Tyrosine | NPHS1 adhesion molecule, nephrin | Homo sapiens |
4 | These observations raise the possibility of an alternate proximal signaling mechanism that might be responsible for nephrin tyrosine phosphorylation. | Tyrosine | NPHS1 adhesion molecule, nephrin | Homo sapiens |
5 | Here we present data showing that integrin engagement at the basal aspect of cultured podocytes results in nephrin tyrosine phosphorylation. | Tyrosine | NPHS1 adhesion molecule, nephrin | Homo sapiens |
6 | Furthermore, nephrin tyrosine phosphorylation was observed in podocytes expressing a membrane-targeted nephrin construct that lacks the extracellular domain. | Tyrosine | NPHS1 adhesion molecule, nephrin | Homo sapiens |
7 | Furthermore, nephrin tyrosine phosphorylation was observed in podocytes expressing a membrane-targeted nephrin construct that lacks the extracellular domain. | Tyrosine | NPHS1 adhesion molecule, nephrin | Homo sapiens |