Title : The β3 Adrenergic Receptor Agonist BRL37344 Exacerbates Atrial Structural Remodeling Through iNOS Uncoupling in Canine Models of Atrial Fibrillation.

Pub. Date : 2016

PMID : 26828873






1 Functional Relationships(s)
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1 Moreover, beta3-AGO reduced BH4 and NO production and increased superoxide production, which was inhibited by the specific iNOS inhibitor, 1400w beta3-AGO also increased iNOS but decreased eNOS and had no effect on nNOS expression in AF. Superoxides nitric oxide synthase 2 Canis lupus familiaris