Title : Photoprotective efficiency of PLGA-curcumin nanoparticles versus curcumin through the involvement of ERK/AKT pathway under ambient UV-R exposure in HaCaT cell line.

Pub. Date : 2016 Apr

PMID : 26803409






1 Functional Relationships(s)
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1 Molecular docking studies suggested that intact curcumin from nanoparticles, bind with BAX in BIM SAHB site and attenuate it to undergo apoptosis while upregulating anti-apoptotic genes like BCL2. Curcumin BCL2 associated X, apoptosis regulator Homo sapiens