Title : Classical and Non-Classical Roles for Pre-Receptor Control of DHT Metabolism in Prostate Cancer Progression.

Pub. Date : 2016 Apr

PMID : 26797685






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In this mini-review, we discuss emerging data that suggest a role for the enzymes mediating pre-receptor control of dihydrotestosterone (DHT) metabolism, including AKR1C2, HSD17B6, HSD17B10, and the UGT family members UGT2B15 and UGT2B17, in controlling intratumoral androgen levels, and thereby influencing PCa progression. Dihydrotestosterone UDP glucuronosyltransferase family 2 member B17 Homo sapiens
2 In this mini-review, we discuss emerging data that suggest a role for the enzymes mediating pre-receptor control of dihydrotestosterone (DHT) metabolism, including AKR1C2, HSD17B6, HSD17B10, and the UGT family members UGT2B15 and UGT2B17, in controlling intratumoral androgen levels, and thereby influencing PCa progression. Dihydrotestosterone UDP glucuronosyltransferase family 2 member B17 Homo sapiens