Pub. Date : 2017 Mar
PMID : 26780783
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Impact of CYP2D6 Polymorphism on Steady-State Plasma Levels of Risperidone and 9-Hydroxyrisperidone in Thai Children and Adolescents with Autism Spectrum Disorder. | Paliperidone Palmitate | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |
| 2 | Additionally, the plasma concentration of risperidone/9-OH risperidone ratio in patients with a CYP2D6 activity score of 0.5 were significantly higher than those with a CYP2D6 activity score of 2 (p = 0.04). | Paliperidone Palmitate | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |
| 3 | The findings indicate that CYP2D6 polymorphisms affect the plasma concentrations of risperidone and the risperidone/9-hydroxyrisperidone ratio. | Paliperidone Palmitate | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |