Title : Expression Levels of DNA Damage Repair Proteins Are Associated With Overall Survival in Platinum-Treated Advanced Urothelial Carcinoma.

Pub. Date : 2016 Aug

PMID : 26778300






2 Functional Relationships(s)
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1 CONCLUSION: A high percentage of nuclear staining of ERCC1, RAD51, and PAR, assessed by immunohistochemistry, correlated with worse OS for patients with mUC treated with first-line platinum combination chemotherapy, supporting the evidence of the DNA repair pathways" role in the prognosis of mUC. Platinum jumping translocation breakpoint Homo sapiens
2 We also report new evidence that RAD51 and PAR might play a role in the platinum response. Platinum jumping translocation breakpoint Homo sapiens