Pub. Date : 2016 Feb
PMID : 26758190
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | MiR-125a regulates chemo-sensitivity to gemcitabine in human pancreatic cancer cells through targeting A20. | gemcitabine | microRNA 125a | Homo sapiens |
| 2 | Over-expression of miR-125a increased the chemo-resistance to gemcitabine in SW1990 cells, while down-regulation of miR-125a in SW1990GZ cells increased chemo-sensitivity to gemcitabine. | gemcitabine | microRNA 125a | Homo sapiens |
| 3 | Over-expression of miR-125a increased the chemo-resistance to gemcitabine in SW1990 cells, while down-regulation of miR-125a in SW1990GZ cells increased chemo-sensitivity to gemcitabine. | gemcitabine | microRNA 125a | Homo sapiens |
| 4 | In conclusion, our results suggest that miR-125a promotes chemo-resistance to gemcitabine in pancreatic cells through targeting A20, which may provide novel therapeutic targets or molecular biomarkers for cancer therapy and improve tumor diagnosis or predictions of therapeutic responses. | gemcitabine | microRNA 125a | Homo sapiens |