Pub. Date : 2016 Jan 13
PMID : 26757638
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Further examination revealed that PC(O-16:0/2:0) similarly promotes a global increase in ceramide accumulation in human neurons which was associated with mitochondrial-derived reactive oxygen species (ROS) and toxicity. | Reactive Oxygen Species | pyruvate carboxylase | Homo sapiens |
2 | Further examination revealed that PC(O-16:0/2:0) similarly promotes a global increase in ceramide accumulation in human neurons which was associated with mitochondrial-derived reactive oxygen species (ROS) and toxicity. | Reactive Oxygen Species | pyruvate carboxylase | Homo sapiens |
3 | These findings suggest that PC(O-16:0/2:0)-dependent mitochondrial dysfunction may be an underlying contributing factor to the ROS production associated with AD. | Reactive Oxygen Species | pyruvate carboxylase | Homo sapiens |