Title : Critical roles of Gi/o proteins and phospholipase C-δ1 in the activation of receptor-operated TRPC4 channels.

Pub. Date : 2016 Jan 26

PMID : 26755577






1 Functional Relationships(s)
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1 Although TRPC3/C6/C7 can be directly activated by diacylglycerols produced by PLC breakdown of phosphatidylinositol 4,5-bisphosphate (PIP2), the mechanism by which the PLC pathway activates TRPC4/C5 remains unclear. Diglycerides transient receptor potential cation channel subfamily C member 3 Homo sapiens