Title : Novel Characteristics of Trypanosoma brucei Guanosine 5'-monophosphate Reductase Distinct from Host Animals.

Pub. Date : 2016 Jan

PMID : 26731263






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Guanosine 5"-monophosphate reductase (GMPR), which catalyzes the deamination of guanosine 5"-monophosphate (GMP) to inosine 5"-monophosphate (IMP), plays an important role in the interconversion of purine nucleotides to maintain the intracellular balance of their concentration. Guanosine Monophosphate guanosine monophosphate reductase Homo sapiens
2 The recombinant protein of T. brucei GMPR catalyzed the conversion of GMP to IMP in the presence of NADPH, and showed apparent affinities for both GMP and NADPH different from those of its mammalian counterparts. Guanosine Monophosphate guanosine monophosphate reductase Homo sapiens