Title : In Vitro and In Vivo Tumor-Targeting siRNA Delivery Using Folate-PEG-appended Dendrimer (G4)/α-Cyclodextrin Conjugates.

Pub. Date : 2016 Mar 16

PMID : 26715308






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Fol-PalphaC (G4, average degree of substitution of alpha-cyclodextrin (DSC) 2.9, average degree of substitution of folate-PEG (DSF) 2)/siRNA complex had the prominent RNAi effect through adequate physicochemical properties, FR-alpha-mediated endocytosis, efficient endosomal escape, and siRNA delivery to cytoplasm with negligible cytotoxicity. Folic Acid rabaptin, RAB GTPase binding effector protein 2 Mus musculus