Title : Mus81 knockdown improves chemosensitivity of hepatocellular carcinoma cells by inducing S-phase arrest and promoting apoptosis through CHK1 pathway.

Pub. Date : 2016 Feb

PMID : 26714930






2 Functional Relationships(s)
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1 Mus81 expression in HepG2 and Bel-7402 HCC cell lines was depleted by lentivirus-mediated short hairpin RNA and the elevated sensitivity of these Mus81-inhibited HCC cells to therapeutic agents, especially to epirubicin (EPI), was evidenced by MTT assay and an HCC chemotherapy mouse model. monooxyethylene trimethylolpropane tristearate MUS81 structure-specific endonuclease subunit Homo sapiens
2 Mus81 expression in HepG2 and Bel-7402 HCC cell lines was depleted by lentivirus-mediated short hairpin RNA and the elevated sensitivity of these Mus81-inhibited HCC cells to therapeutic agents, especially to epirubicin (EPI), was evidenced by MTT assay and an HCC chemotherapy mouse model. monooxyethylene trimethylolpropane tristearate MUS81 structure-specific endonuclease subunit Homo sapiens